CME on Transplantation is dedicated to online CME conferences, courses and presentations (slides with voice over) on transplantation, given by local and international experts. Its mission is to keep you up-to-date with the most recent developments on transplantation.
Presentation
"Steroid Minimization Protocols" Dr. Edward H. Cole (biography) English - 2004-02-02 - 37 minutes
(58 slides)
Summary : In this presentation Dr Cole presents the latest data available on steroid minimization protocols, in a discussion about their associated risks and benefits; in which patients they may be utilised; and whether steroid avoidance (a short steroid course of 0 to 7 days) is preferable to later steroid withdrawal.
Randomized trials have shown an increase in acute rejection rates with steroid withdrawal (1, 2), although other protocols might achieve better results. Short-term data show steroid avoidance to be safe and effective in low immunologic risk patients, and as having other clinical benefits which will be discussed here.
Learning objectives : The participant will learn about steroid minimization protocols:
Benefits of Steroid Minimization
Steroid Withdrawal versus Avoidance:
- Risks vs benefits
-->Acute rejection
-->Renal function
-->Graft and patient survival
-->Freedom from adverse events
Conclusions
Outstanding Issues